Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691386 | 0.96 | CASP3 (0.68) | CASP3CA12CA1CA2CA9 | |
| SCHEMBL4424839 | 0.93 | CES2 (0.61) | CASP3CA12CA1CA2CA9 | |
| SCHEMBL4424799 | 0.91 | CASP3 (0.79) | CASP3CA12CA1CA2CA9 | |
| SCHEMBL6287318 | 0.91 | RPS6KA2 (0.58) | CASP3CA12CA1CA2CA9 | |
| SCHEMBL30472950 | 0.87 | CASP3 (0.85) | CASP3CA12CA1CA2CA9 | |
| SCHEMBL326305 | 0.87 | CASP3 (0.85) | CASP3CA12CA1CA2CA9 | |
| SCHEMBL4415503 | 0.87 | CHRM5 (0.65) | CASP3CA12CA1CA2CA9 | |
| SCHEMBL9053599 | 0.86 | CASP3 (0.65) | CASP3CA12CA1CA2CA9 | |
| SCHEMBL29820192 | 0.86 | CASP3 (0.65) | CASP3CA12CA1CA2CA9 | |
| SCHEMBL18668950 | 0.86 | CES2 (0.67) | CASP3CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4370486-A | Biphenyl compounds, a process for their preparation and their use as intermediate products for optical brighteners, dyestuffs, plastics and medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1983-01-25 | — | — | US | disclosed |
| EP-0047877-A2 | Biphenyl compounds and process for their preparation | BAYER AG (DE) | 1982-03-24 | — | — | EP | disclosed |