Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TOP2A | P11388 | 2/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190788 | 0.80 | CRBN (0.38) | CRBNALDH1A1TOP2ATOP2BMAPT | |
| SCHEMBL10617825 | 0.73 | KDM4E (0.35) | CRBNALDH1A1TOP2ATOP2BMAPT | |
| SCHEMBL6534633 | 0.73 | TOP2A (0.44) | CRBNALDH1A1TOP2ATOP2BMAPT | |
| SCHEMBL6534567 | 0.73 | TOP2A (0.44) | CRBNALDH1A1TOP2ATOP2BMAPT | |
| SCHEMBL13349250 | 0.73 | TOP2A (0.44) | CRBNALDH1A1TOP2ATOP2BMAPT | |
| SCHEMBL10976401 | 0.73 | CRBN (0.38) | CRBNALDH1A1TOP2ATOP2BMAPT | |
| SCHEMBL11531176 | 0.73 | CRBN (0.38) | CRBNALDH1A1TOP2ATOP2BMAPT | |
| SCHEMBL5269923 | 0.72 | CRBN (0.45) | CRBNALDH1A1TOP2ATOP2BMAPT | |
| SCHEMBL11598867 | 0.72 | CRBN (0.40) | CRBNALDH1A1TOP2ATOP2BMAPT | |
| SCHEMBL16685437 | 0.72 | CRBN (0.40) | CRBNALDH1A1TOP2ATOP2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4395542-A | EVAPORATIVE STRIPPING | CIBA-GEIGY CORPORATION (US) | 1983-07-26 | — | — | US | disclosed |