SCHEMBL5269923

SCHEMBL5269923

CCC(S)N1CC(=O)NC1=O

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.45
TOP2A P11388 3/20 0.38
TOP2B Q02880 3/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PTGS1 P23219 2/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6534633 0.78 TOP2A (0.44) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL6534567 0.78 TOP2A (0.44) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL5073235 0.76 CRBN (0.40) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL11598867 0.76 CRBN (0.40) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL16685437 0.76 CRBN (0.40) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL10764977 0.76 CRBN (0.40) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL11082931 0.76 CRBN (0.40) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL9190788 0.73 CRBN (0.38) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL11167481 0.72 CRBN (0.36) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL378251 0.72 TOP2A (0.50) CRBNTOP2ATOP2BALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109485589-A Method for preparing zinc methionine chelate from methionine mother liquor containing potassium carbonate or potassium bicarbonate 禄丰天宝磷化工有限公司 2019-03-19 CN claimed
CN-106432020-B A kind of D, the isolation and purification method of L-Methionine 宁夏紫光天化蛋氨酸有限责任公司 2018-11-20 CN claimed
CN-108658820-A Reduce the methionine production method of by-product sodium sulphate 宁夏紫光天化蛋氨酸有限责任公司 2018-10-16 CN claimed
CN-106565608-A Preparation method of highly-pure 5-(2-methylthioethyl)-hydantoin 宁夏紫光天化蛋氨酸有限责任公司 2017-04-19 CN claimed
CN-106349131-A Separation and purification method of methionine 宁夏紫光天化蛋氨酸有限责任公司 2017-01-25 CN claimed
CN-103694177-B Hydrocyanic acid gaseous mixture is utilized to produce 5-(2-methylmercaptoethyl continuously) method of-hydantoin and device thereof 宁夏紫光天化蛋氨酸有限责任公司 2017-01-04 CN claimed
JP-54132521-A None JP disclosed
CN-110423209-A Method for synthesizing methionine by continuously and rapidly alkaline hydrolyzing 5- (beta-methylmercapto ethyl) -hydantoin LUFENG TIANBAO PHOSPHORUS CHEMICAL CO LTD 2019-11-08 CN disclosed
CN-109734637-A Methionine crystallization mother liquor treatment method 禄丰天宝磷化工有限公司 2019-05-10 CN disclosed
CN-109678769-A Method for producing methionine metal chelate by comprehensively utilizing methionine crystallization mother liquor 禄丰天宝磷化工有限公司 2019-04-26 CN disclosed
CN-109678768-A Method for producing methionine metal chelate by using methionine crystallization mother liquor 禄丰天宝磷化工有限公司 2019-04-26 CN disclosed
CN-108658819-A A kind of clean preparation method of methionine 宁夏紫光天化蛋氨酸有限责任公司 2018-10-16 CN disclosed
CN-106565608-A Preparation method of highly-pure 5-(2-methylthioethyl)-hydantoin 宁夏紫光天化蛋氨酸有限责任公司 2017-04-19 CN disclosed
CN-103694177-B Hydrocyanic acid gaseous mixture is utilized to produce 5-(2-methylmercaptoethyl continuously) method of-hydantoin and device thereof 宁夏紫光天化蛋氨酸有限责任公司 2017-01-04 CN disclosed
CN-101629160-B Microorganism producing L-methionine precursor and method of producing l-methionine precursor using the microorganism CJ CHEILJEDANG CORP 2013-03-20 CN disclosed
CN-101629160-A Microorganism producing L-methionine precursor and method of producing l-methionine precursor using the microorganism CJ CHEILJEDANG CORP 2010-01-20 CN disclosed
EP-1840119-A2 Process for producing methionine Sumitomo Chemical Company, Limited (JP) 2007-10-03 EP disclosed
US-20070225523-A1 Hydrolysis of 5-( beta -methylmercaptoethyl)hydantoin in the presence of an alkali such potassium carbonate, potassium bicarbonate and potassium hydroxide, crystallizing the hydrolyzate under pressure of carbonic acid gas; corrosion of an apparatus is prevented SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-09-27 US disclosed
JP-S54132521-A PREPARATION OF COLORLESS METHIONINE SUMITOMO CHEM CO LTD 1979-10-15 JP disclosed