Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | CFD | P00746 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylamine SCHEMBL2841170 | 0.87 | LOXL2 (0.78) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL2841167 | 0.87 | LOXL2 (0.78) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL28177368 | 0.87 | CYP2D6 (0.56) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL29016376 | 0.86 | LOXL2 (0.67) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL25352130 | 0.85 | LOXL2 (0.74) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL6429492 | 0.85 | LOXL2 (0.74) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL3188490 | 0.85 | LOXL2 (0.74) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL8464909 | 0.85 | LOXL2 (0.74) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL3891720 | 0.85 | LOXL2 (0.74) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL9567530 | 0.85 | LOXL2 (0.74) | LOXL2CYP1A2CYP2D6CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421914-A | IMMUNE FUNCTION REGULATORS | TEIJIN LIMITED (JP) | 1983-12-20 | — | — | US | disclosed |
| EP-0049902-A2 | Novel thiazolo(3,2-a)pyrimidines, derivatives thereof, processes for production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1982-04-21 | — | — | EP | disclosed |