Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333039 | 0.78 | KDM4E (0.31) | KDM4E | |
| SCHEMBL11173756 | 0.77 | — | — | |
| SCHEMBL11171250 | 0.72 | AHR (0.45) | ADRA2AADRA2BADRA2C | |
| SCHEMBL11165155 | 0.72 | DRD2 (0.40) | — | |
| SCHEMBL11178567 | 0.72 | AHR (0.45) | ADRA2AADRA2BADRA2C | |
| SCHEMBL11171302 | 0.72 | HTR5A (0.41) | — | |
| SCHEMBL11170068 | 0.70 | BRD4 (0.42) | KDM4E | |
| SCHEMBL11178580 | 0.69 | PDE3B (0.47) | — | |
| SCHEMBL11162677 | 0.69 | HTR5A (0.46) | — | |
| SCHEMBL7207961 | 0.66 | AKR1B1 (0.40) | ADRA2AADRA2BADRA2CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4372956-A | CARDIOTONIC AGENTS, VASODILATION | SANDOZ LTD. (CH) | 1983-02-08 | — | — | US | claimed |