Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29433775 | 0.70 | CA9 (0.47) | KDM4ELMNACYP3A4ALDH1A1ADRA2A | |
| SCHEMBL11169596 | 0.66 | ADRA2A (0.35) | KDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL28346622 | 0.63 | BRD4 (0.38) | — | |
| SCHEMBL3254446 | 0.63 | BRD4 (0.38) | — | |
| SCHEMBL10814721 | 0.61 | CYP3A4 (0.37) | KDM4EACHELMNACYP3A4HTR1A | |
| SCHEMBL13806532 | 0.61 | PDE3B (0.41) | CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL23671556 | 0.61 | LMNA (0.44) | AKR1B1KDM4ELMNACYP3A4ALDH1A1 | |
| SCHEMBL5787017 | 0.61 | CES1 (0.50) | KDM4EALDH1A1 | |
| SCHEMBL10910494 | 0.60 | MAPT (0.51) | KDM4EACHELMNACYP3A4HTR1A | |
| SCHEMBL9739278 | 0.60 | LMNA (0.40) | AKR1B1LMNACYP3A4ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987255-B1 | Substituted aminoquinazolinone (thione) derivatives | NIHON NOHYAKU CO LTD (JP) | 2003-07-16 | — | — | EP | disclosed |
| EP-0735035-B1 | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same | NIHON NOHYAKU CO LTD (JP) | 2002-06-05 | — | — | EP | disclosed |
| EP-0987255-A2 | Substituted aminoquinazolinone (thione) derivatives | NIHON NOHYAKU CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5714492-A | INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1998-02-03 | — | — | US | disclosed |
| EP-0735035-A1 | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same | NIHON NOHYAKU CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |