Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51941 | 0.84 | ALDH1A1 (0.43) | TSHRLMNAALDH1A1KMT2AMAPT | |
| SCHEMBL51134 | 0.84 | TSHR (0.41) | TSHRLMNAALDH1A1KMT2AMAPT | |
| SCHEMBL51834 | 0.83 | TSHR (0.40) | TSHRLMNAALDH1A1KMT2AMAPT | |
| SCHEMBL9455916 | 0.83 | TSHR (0.40) | TSHRLMNAALDH1A1KMT2AMAPT | |
| SCHEMBL9456118 | 0.82 | TSHR (0.50) | TSHRLMNAALDH1A1KMT2AMAPT | |
| SCHEMBL11173009 | 0.81 | HSP90AA1 (0.38) | TSHRALDH1A1KMT2AMAPTHSP90AA1 | |
| SCHEMBL10831575 | 0.81 | SMN1; SMN2 (0.42) | TSHRLMNAALDH1A1KMT2AMAPT | |
| SCHEMBL10806484 | 0.80 | TSHR (0.38) | TSHRALDH1A1KMT2AMAPTHSP90AA1 | |
| SCHEMBL10830507 | 0.78 | TSHR (0.36) | TSHRLMNAALDH1A1KMT2AMAPT | |
| SCHEMBL10940647 | 0.78 | HTR6 (0.33) | LMNAALDH1A1POLBKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4385182-A | SENSITIZERS OR PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |