Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941810 | 0.88 | ALDH1A1 (0.36) | NPC1MAPTMEN1KMT2ALMNA | |
| SCHEMBL11165237 | 0.88 | LMNA (0.40) | NPC1MAPTHIF1AMEN1CYP1A2 | |
| SCHEMBL10939093 | 0.85 | ALDH1A1 (0.34) | CACNA1FCACNA1DCACNA1SCACNA1CMAPT | |
| SCHEMBL10830507 | 0.85 | TSHR (0.36) | SMN1; SMN2CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9456118 | 0.84 | TSHR (0.50) | SMN1; SMN2MAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL51941 | 0.84 | ALDH1A1 (0.43) | SMN1; SMN2NPC1MAPTMEN1CYP1A2 | |
| SCHEMBL51134 | 0.84 | TSHR (0.41) | MAPTMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10939109 | 0.83 | HSP90AA1 (0.45) | SMN1; SMN2NPC1MAPTMEN1CYP1A2 | |
| SCHEMBL9455916 | 0.83 | TSHR (0.40) | SMN1; SMN2MAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL51834 | 0.83 | TSHR (0.40) | SMN1; SMN2NPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564578-A | PHOTOSENSITIVE EPOXY RESINS | CIBA-GEIGY CORPORATION (US) | 1986-01-14 | — | — | US | disclosed |
| US-4560643-A | BLEND OF AROMATIC KETONE, POLYMER, AND GROUP IB OR EIGHT METAL SALT | CIBA GEIGY CORPORATION (US) | 1985-12-24 | — | — | US | disclosed |
| US-4385182-A | SENSITIZERS OR PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |