Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 8/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065215 | 1.00 | HTT (0.38) | HTTACELMNAFFAR2HSD17B10 | |
| SCHEMBL11110245 | 0.86 | HSD17B10 (0.48) | HTTACELMNAFFAR2HSD17B10 | |
| SCHEMBL11248466 | 0.84 | FFAR2 (0.44) | HTTACELMNAFFAR2HSD17B10 | |
| SCHEMBL11068375 | 0.82 | POLB (0.44) | HTTACELMNAFFAR2HSD17B10 | |
| SCHEMBL11067693 | 0.82 | ACE (0.41) | HTTACELMNAFFAR2HSD17B10 | |
| SCHEMBL11062261 | 0.82 | ACE (0.56) | HTTACELMNAFFAR2POLB | |
| SCHEMBL11184480 | 0.81 | FFAR2 (0.52) | HTTACELMNAFFAR2HSD17B10 | |
| SCHEMBL11067697 | 0.80 | ACE (0.43) | HTTACELMNAFFAR2HSD17B10 | |
| SCHEMBL11234757 | 0.79 | KDM4E (0.41) | FFAR2HSD17B10 | |
| SCHEMBL11169739 | 0.79 | ACE (0.49) | HTTACELMNAFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4386096-A | ANGIOTENSIN-CONVERTING ENZYME INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1983-05-31 | — | — | US | claimed |