Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110245 | 0.90 | HSD17B10 (0.48) | ALDH1A1FFAR2HSD17B10 | |
| SCHEMBL11248466 | 0.89 | FFAR2 (0.44) | ALDH1A1FFAR2HSD17B10 | |
| SCHEMBL11068375 | 0.84 | POLB (0.44) | ALDH1A1FFAR2HSD17B10 | |
| SCHEMBL11066449 | 0.84 | HTT (0.44) | ALDH1A1FFAR2HSD17B10 | |
| SCHEMBL11247271 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11189829 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11062261 | 0.80 | ACE (0.56) | ALDH1A1FFAR2 | |
| SCHEMBL11234749 | 0.80 | ACE (0.47) | KDM4EALDH1A1FFAR2HSD17B10 | |
| SCHEMBL11065215 | 0.79 | HTT (0.38) | FFAR2HSD17B10 | |
| SCHEMBL11169752 | 0.79 | HTT (0.38) | FFAR2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356183-A | ENZYME INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-10-26 | — | — | US | claimed |