SCHEMBL11170010

SCHEMBL11170010

Cc1cc(Oc2nc(Oc3cc(C)c(O)c(C(C)(C)C)c3)nc(Oc3cc(C)c(O)c(C(C)(C)C)c3)n2)cc(C(C)(C)C)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.53
CYP2C19 P33261 2/20 0.53
CYP1A2 P05177 1/20 0.53
CA2 P00918 3/20 0.48
CA1 P00915 2/20 0.48
SMN1; SMN2 Q16637 3/20 0.44
ALDH1A1 P00352 2/20 0.44
POLB P06746 1/20 0.44
TYR P14679 1/20 0.44
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
HPN P05981 1/20 0.40
MAPT P10636 1/20 0.40
ALOX15 P16050 1/20 0.40
SIRT5 Q9NXA8 1/20 0.40
ESRRA P11474 3/20 0.40
MEN1 O00255 1/20 0.37
GALR3 O60755 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49624 0.89 CA2 (0.61) CYP2C9CYP2C19CYP1A2CA2CA1
SCHEMBL30564889 0.81 CA2 (0.52) CYP2C9CYP2C19CYP1A2CA2CA1
SCHEMBL11176332 0.81 CYP1A2 (0.36) CYP2C9CYP2C19CYP1A2CA2CA1
SCHEMBL10954074 0.79 CA2 (0.77) CYP2C9CYP2C19CYP1A2CA2CA1
SCHEMBL7029038 0.79 CA2 (0.53) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL11184986 0.78 CYP1A2 (0.36) CYP2C9CYP2C19CYP1A2CA2CA1
SCHEMBL8996529 0.77 CA2 (0.52) CYP2C9CYP2C19CYP1A2CA2CA1
SCHEMBL9008266 0.76 ESRRA (0.59) CYP2C9CYP1A2SMN1; SMN2ALDH1A1POLB
SCHEMBL5082754 0.76 CA2 (0.71) CYP2C9CYP2C19CYP1A2CA2CA1
SCHEMBL27501380 0.76 GABRA1 (0.54) CYP2C9CYP2C19CYP1A2CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE31343-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
US-RE31342-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
EP-0018015-A1 Stabilized polyolefins filled with talc EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-10-29 EP disclosed
US-4208522-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1980-06-17 US disclosed
US-4130710-A POLYOLEFIN STABILIZERS CIBA-GEIGY CORPORATION (US) 1978-12-19 US disclosed
US-4125517-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1978-11-14 US disclosed
US-4110305-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1978-08-29 US disclosed
US-4070335-A 3,5-Dialkyl-4-hydroxyphenylalkyl substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1978-01-24 US disclosed
US-4067848-A Alkyl alkanoate derivatives of substituted piperazine-diones and polymer compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1978-01-10 US disclosed
US-4051137-A Substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1977-09-27 US disclosed
US-4028334-A STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1977-06-07 US disclosed
US-4007157-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1977-02-08 US disclosed
US-4007156-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1977-02-08 US disclosed
US-3992351-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1976-11-16 US disclosed
US-3969316-A 3,5-Dialkyl-4-hydroxyphenylalkyl substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1976-07-13 US disclosed
US-3968078-A Alkyl alkanoate derivatives of substituted piperazine-diones and polymer compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1976-07-06 US disclosed
US-3937711-A POLYMERIC STABILIZERS, POLYOLEFINS CIBA-GEIGY CORPORATION (US) 1976-02-10 US disclosed
US-3936456-A Substituted piperazine dione oxyls and hydroxides and polymer compositions stabilized thereby CIBY-GEIGY CORPORATION (US) 1976-02-03 US disclosed