Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49624 | 0.87 | CA2 (0.61) | CA2CA1HPNMAPTALOX15 | |
| SCHEMBL30564889 | 0.79 | CA2 (0.52) | CA2CA1HPNMAPTALOX15 | |
| SCHEMBL5082754 | 0.79 | CA2 (0.71) | CA2CA1HPNMAPTALOX15 | |
| SCHEMBL11170010 | 0.77 | CYP2C9 (0.53) | CA2CA1HPNMAPTALOX15 | |
| SCHEMBL7029038 | 0.77 | CA2 (0.53) | CA2CA1HPNMAPTALOX15 | |
| SCHEMBL11868254 | 0.75 | CA2 (0.57) | CA2CA1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL3126079 | 0.74 | CA2 (0.53) | CA2CA1HPNMAPTALOX15 | |
| SCHEMBL10631750 | 0.74 | CA2 (0.63) | CA2CA1HPNMAPTALOX15 | |
| SCHEMBL10639221 | 0.71 | ALDH1A1 (0.36) | MAPTALOX15SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8996373 | 0.71 | HPN (0.50) | CA2CA1HPNMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578667-A | PHOTOSTABILITY, HEAT RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| EP-0703227-A1 | Watersoluble antioxidants, process of their preparation, and their use for the photochemical and thermical stabilisation of polyamide fibers | CIBA-GEIGY AG (CH) | 1996-03-27 | — | — | EP | disclosed |