Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | HRAS | P01112 | 1/20 | 0.38 |
| ▸ | MAG | P20916 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9472134 | 0.90 | MAPK1 (0.54) | MAPK1NOD2TACR2HRASMAG | |
| SCHEMBL11170170 | 0.88 | MAPK1 (0.65) | MAPK1NOD2TACR2HRASMAG | |
| SCHEMBL11590979 | 0.85 | MAPK1 (0.37) | MAPK1TACR2TP53MDM2L3MBTL1 | |
| SCHEMBL7774709 | 0.84 | MAPK1 (0.50) | MAPK1TACR2HRASLGALS8LGALS3 | |
| SCHEMBL11591229 | 0.81 | MAPK1 (0.34) | MAPK1MAGALDH1A1L3MBTL1MMP12 | |
| SCHEMBL13491610 | 0.80 | MAPK1 (0.48) | MAPK1TACR2HRASLGALS8LGALS3 | |
| SCHEMBL31134199 | 0.79 | MAPK1 (0.58) | MAPK1HRASMAGLGALS8LGALS3 | |
| SCHEMBL8822997 | 0.79 | MAPK1 (0.58) | MAPK1HRASMAGLGALS8LGALS3 | |
| SCHEMBL1149280 | 0.77 | HRAS (0.47) | MAPK1TACR2HRASMAGLGALS8 | |
| SCHEMBL11170361 | 0.75 | MAPK1 (0.50) | MAPK1NOD2HRASTP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101536-A | IMMUNOADJUVANT, ANTITUMOR | DAIICHI SEIYAKU CO., LTD. (JP) | 1978-07-18 | — | — | US | disclosed |