Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.41 |
| ▸ | HTR1A | P08908 | 7/20 | 0.41 |
| ▸ | HTR7 | P34969 | 7/20 | 0.41 |
| ▸ | HTR5A | P47898 | 7/20 | 0.41 |
| ▸ | HTR1D | P28221 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 4/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11170515 | 0.81 | BRD4 (0.44) | HTR2CHTR1AHTR7HTR5AHTR1D | |
| SCHEMBL22279675 | 0.80 | CREBBP (0.41) | HTR2CHTR5AADRA2AADRA2BADRA2C | |
| SCHEMBL24814721 | 0.79 | BRD4 (0.35) | BRD4CREBBPMEN1GAAKMT2A | |
| SCHEMBL11162775 | 0.79 | NOTUM (0.50) | HTR2CHTR1AHTR7HTR5AHTR1D | |
| SCHEMBL30047998 | 0.79 | BRD4 (0.35) | BRD4CREBBPMEN1GAAKMT2A | |
| SCHEMBL16729472 | 0.79 | DRD2 (0.41) | HTR1AHTR7 | |
| SCHEMBL14826475 | 0.78 | ALDH1A1 (0.35) | BRD4CREBBPEP300 | |
| Bromide SCHEMBL16717336 | 0.77 | DRD2 (0.40) | HTR1AHTR7 | |
| Bromide SCHEMBL16717340 | 0.77 | DRD2 (0.40) | HTR1AHTR7 | |
| SCHEMBL30330058 | 0.76 | MTNR1A (0.52) | HTR1AHTR5AADRA2ACYP2D6ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4416884-A | ANTIBIOTIC, BACTERICIDE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-22 | — | — | US | disclosed |
| US-4014877-A | MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1977-03-29 | — | — | US | disclosed |
| US-4001243-A | ANTI-MICROBIAL | RIKER LABORATORIES, INC. (US) | 1977-01-04 | — | — | US | disclosed |
| US-3985882-A | ADMISTERING | RIKER LABORATORIES, INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3969463-A | MICROBIOCIDE | RIKER LABORATORIES, INC. (US) | 1976-07-13 | — | — | US | disclosed |