SCHEMBL11170282

SCHEMBL11170282

C=CC[n+]1c(C)cc(N)c2ccccc21

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 13/20 0.63
MEN1 O00255 4/20 0.63
GMNN O75496 4/20 0.63
LMNA P02545 4/20 0.63
POLB P06746 4/20 0.63
MAPT P10636 4/20 0.63
APEX1 P27695 4/20 0.63
RECQL P46063 4/20 0.63
BLM P54132 4/20 0.63
PMP22 Q01453 4/20 0.63
KMT2A Q03164 4/20 0.63
SMN1; SMN2 Q16637 4/20 0.63
NPSR1 Q6W5P4 4/20 0.63
TDP1 Q9NUW8 4/20 0.63
ALDH1A1 P00352 3/20 0.63
TP53 P04637 3/20 0.63
CYP3A4 P08684 3/20 0.63
HSD17B10 Q99714 3/20 0.63
KDM4E B2RXH2 3/20 0.63
CYP2D6 P10635 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9976326 0.85 PRKCA (0.73) PRKCAMEN1GMNNLMNAPOLB
SCHEMBL12903653 0.82 PRKCA (0.84) PRKCAMEN1GMNNLMNAPOLB
Dequalinium SCHEMBL29557297 0.78 PRKCA (1.00) PRKCAMEN1GMNNLMNAPOLB
SCHEMBL6305111 0.78 PRKCA (1.00) PRKCAMEN1GMNNLMNAPOLB
Dequalinium SCHEMBL149457 0.78 PRKCA (1.00) PRKCAMEN1GMNNLMNAPOLB
SCHEMBL6298118 0.78 PRKCA (1.00) PRKCAMEN1GMNNLMNAPOLB
SCHEMBL6299633 0.78 PRKCA (1.00) PRKCAMEN1GMNNLMNAPOLB
Dequalinium SCHEMBL29577841 0.78 PRKCA (1.00) PRKCAMEN1GMNNLMNAPOLB
Dequalinium SCHEMBL581602 0.77 MEN1 (0.94) PRKCAMEN1GMNNLMNAPOLB
Dequalinium SCHEMBL4625714 0.77 MEN1 (0.94) PRKCAMEN1GMNNLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE31397-E NONSTAINING BEECHAM INC. (US) 1983-09-27 US claimed
US-4256731-A COMPRISING A CATIONIC MICROBIOCIDE AND A QUATERNARY AMMONIUM COMPOUND ALONG WITH INHIBITION DISCOLORATION-COMPOUNDS WHICH INCLUDE A NONIONIC SURFACTANT AND AN AMINO ACID OR A DI- OR TRICARBOXYLIC ACID BEECHAM, INC. (US) 1981-03-17 US claimed
US-4213961-A Oral compositions BEECHAM, INC. (US) 1980-07-22 US claimed
US-4183916-A BISBIGUANIDE OR QUATERNARY AMMONIUM ANTICARIES AGENT, MALIC ACID AS ANTISTAINING AGENT BEECHAM INC. (US) 1980-01-15 US claimed
EP-0004719-A2 Oral hygiene compositions BEECHAM INC. (US) 1979-10-17 EP claimed
US-RE31397-E NONSTAINING BEECHAM INC. (US) 1983-09-27 US disclosed
US-4256731-A COMPRISING A CATIONIC MICROBIOCIDE AND A QUATERNARY AMMONIUM COMPOUND ALONG WITH INHIBITION DISCOLORATION-COMPOUNDS WHICH INCLUDE A NONIONIC SURFACTANT AND AN AMINO ACID OR A DI- OR TRICARBOXYLIC ACID BEECHAM, INC. (US) 1981-03-17 US disclosed
US-4213961-A Oral compositions BEECHAM, INC. (US) 1980-07-22 US disclosed
US-4183916-A BISBIGUANIDE OR QUATERNARY AMMONIUM ANTICARIES AGENT, MALIC ACID AS ANTISTAINING AGENT BEECHAM INC. (US) 1980-01-15 US disclosed
EP-0004719-A2 Oral hygiene compositions BEECHAM INC. (US) 1979-10-17 EP disclosed