Dequalinium

Dequalinium

SCHEMBL581602

C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.Cc1cc(N)c2ccccc2[n+]1CCCCCCCCCC[n+]1c(C)cc(N)c2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Dequalinium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.91
CHRM1 known ✓ P11229 1/20 0.91
ACHE known ✓ P22303 1/20 0.91
SLC6A2 known ✓ P23975 1/20 0.91
SLC6A3 known ✓ Q01959 1/20 0.91
MEN1 O00255 4/20 0.94
GMNN O75496 4/20 0.94
LMNA P02545 4/20 0.94
POLB P06746 4/20 0.94
MAPT P10636 4/20 0.94
APEX1 P27695 4/20 0.94
RECQL P46063 4/20 0.94
BLM P54132 4/20 0.94
PMP22 Q01453 4/20 0.94
KMT2A Q03164 4/20 0.94
SMN1; SMN2 Q16637 4/20 0.94
NPSR1 Q6W5P4 4/20 0.94
TDP1 Q9NUW8 4/20 0.94
TP53 P04637 3/20 0.94
CYP3A4 P08684 3/20 0.94

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dequalinium SCHEMBL4625714 1.00 MEN1 (0.94) MEN1GMNNLMNAPOLBMAPT
Dequalinium SCHEMBL29613054 0.97 MEN1 (1.00) MEN1GMNNLMNAPOLBMAPT
Dequalinium SCHEMBL2544854 0.97 MEN1 (1.00) MEN1GMNNLMNAPOLBMAPT
Dequalinium SCHEMBL34043 0.97 MEN1 (1.00) MEN1GMNNLMNAPOLBMAPT
Dequalinium SCHEMBL29380717 0.97 MEN1 (1.00) MEN1GMNNLMNAPOLBMAPT
Dequalinium SCHEMBL3967999 0.95 MEN1 (0.97) MEN1GMNNLMNAPOLBMAPT
Dequalinium SCHEMBL149457 0.95 PRKCA (1.00) MEN1GMNNLMNAPOLBMAPT
SCHEMBL6298118 0.95 PRKCA (1.00) MEN1GMNNLMNAPOLBMAPT
SCHEMBL6299633 0.95 PRKCA (1.00) MEN1GMNNLMNAPOLBMAPT
Dequalinium SCHEMBL29577841 0.95 PRKCA (1.00) MEN1GMNNLMNAPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 519 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105585530-B Preparation method of imidazoline 中国石油化工股份有限公司 2020-05-19 CN claimed
EP-3037511-A1 SEMI-AQUEOUS PHOTORESIST OR SEMICONDUCTOR MANUFACTURING RESIDUE STRIPPING AND CLEANING COMPOSITION WITH IMPROVED SILICON PASSIVATION AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-06-29 EP claimed
US-20160179011-A1 Semi-Aqueous Photoresist or Semiconductor Manufacturing Residue Stripping and Cleaning Composition with Improved Silicon Passivation AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-06-23 US claimed
US-20260146127-A1 COPOLYESTER DERIVED FROM 3-HYDROXYBUTYRIC ACID AND METHOD FOR PRODUCING SAME DIC CORPORATION (JP) 2026-05-28 US disclosed
EP-4149979-B1 ALKYLATED AROMATIC COMPOUNDS FOR HIGH VISCOSITY APPLICATIONS EXXONMOBIL CHEMICAL PATENTS INC (US) 2026-05-27 EP disclosed
US-20260015530-A1 ADHESIVE COMPOSITION, ORGANIC FIBER MATERIAL, RUBBER ARTICLE, ORGANIC FIBER-RUBBER COMPOSITE, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-01-15 US disclosed
US-20250304744-A1 COPOLYESTER RESIN AND METHOD FOR PRODUCING SAME DIC CORPORATION (JP) 2025-10-02 US disclosed
US-20250236734-A1 CROSSLINKABLE ASPHALT COMPOSITIONS AND RELATED SYSTEMS AND RELATED METHODS BMRC LLC (US) 2025-07-24 US disclosed
EP-4567056-A1 COPOLYESTER COMPRISING 3-HYDROXYBUTYRIC ACID AND METHOD FOR PRODUCING SAME DIC Corporation (JP) 2025-06-11 EP disclosed
EP-4563670-A1 ADHESIVE COMPOSITION, ORGANIC FIBROUS MATERIAL, RUBBER ARTICLE, ORGANIC FIBER/RUBBER COMPOSITE, AND TIRE BRIDGESTONE CORPORATION (JP) 2025-06-04 EP disclosed
EP-4545481-A1 CARBON DIOXIDE FIXATION DEVICE AND BATTERY Liberal LLC (JP) 2025-04-30 EP disclosed
US-4231759-A ANTIDEPOSIT AGENTS COMPRISING A PHENOL-, AMINE-, AND ALDEHYDE-MODIFIED POLYALKYLENE POLYMER STANDARD OIL COMPANY (INDIANA) (US) 1980-11-04 US disclosed
US-4094800-A ADDITIVES COMPRISING A BASIC ZINC ALKYL DITHIOPHOSPHATE AND REACTION PRODUCT OF ALKENYL SUCCINIC ANHYDRIDE WITH AN ALCOHOL OR AMINE STANDARD OIL COMPANY (INDIANA) (US) 1978-06-13 US disclosed
US-4028143-A Wax-flux composition containing a succinimide salt of an alkylaryl sulfonic acid for soldering CHEVRON RESEARCH COMPANY (US) 1977-06-07 US disclosed
US-4000162-A DETERGENT, DISPERSANT FOR LUBRICATING OILS TEXACO INC. (US) 1976-12-28 US disclosed
US-3985802-A PHENOL- FORMALDEHYDE-AMINO SUBSTITUTED UREA STANDARD OIL COMPANY (INDIANA) (US) 1976-10-12 US disclosed
US-3968311-A Metal coated with compositions prepared from aqueous dispersions of carboxylic acid resin and an aliphatic amine CONTINENTAL CAN COMPANY, INC. (US) 1976-07-06 US disclosed
US-3960889-A DETERGENT-DISPERSANT IN OIL AND HYDROCARBON LUBRICANT TEXACO INC. (US) 1976-06-01 US disclosed
US-3954494-A Wax-flux composition containing a succinimide salt of an alkylaryl sulfonic acid for soldering CHEVRON RESEARCH COMPANY (US) 1976-05-04 US disclosed
US-3951977-A MINERAL OIL SOLUBLE, ANTIWEAR, ANTIRUST, DISPERSION DETERGENT ADDITIVES STANDARD OIL COMPANY (US) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146127-A1 COPOLYESTER DERIVED FROM 3-HYDROXYBUTYRIC ACID AND METHOD FOR PRODUCING SAME HAO2, HAAO, HACD3 CHRM2 2533/4885CHRM1 2862/4885ACHE 2753/4885
US-20260015530-A1 ADHESIVE COMPOSITION, ORGANIC FIBER MATERIAL, RUBBER ARTICLE, ORGANIC FIBER-RUBBER COMPOSITE, AND TIRE ILK, VIM, MSN CHRM2 346/4885CHRM1 137/4885ACHE 1344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.