Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41054 | 0.83 | TSHR (0.40) | — | |
| SCHEMBL16500668 | 0.73 | KDM4E (0.47) | KDM4E | |
| SCHEMBL6466586 | 0.73 | KDM4E (0.47) | KDM4E | |
| SCHEMBL17867144 | 0.68 | KDM4E (0.43) | KDM4E | |
| SCHEMBL13637393 | 0.67 | KDM4E (0.39) | KDM4E | |
| SCHEMBL18751776 | 0.66 | ABCB1 (0.36) | — | |
| SCHEMBL17867288 | 0.66 | SOAT1 (0.43) | KDM4E | |
| SCHEMBL13399582 | 0.66 | ABCB1 (0.36) | — | |
| SCHEMBL13290575 | 0.66 | ABCB1 (0.36) | — | |
| SCHEMBL6439632 | 0.66 | ABCB1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3980653-A | Process for the production of 3,6-bis-(2-methylmercaptoethyl)-2,5-piperazinedione | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-09-14 | — | — | US | claimed |
| US-20180194804-A1 | SIMPLIFIED AND SCALABLE METHOD FOR SYNTHESIS OF 2,6-BIS(METHIONYL)- 1,4-DIKETOPIPERAZINE | EVONIK DEGUSSA GMBH (DE) | 2018-07-12 | — | — | US | disclosed |
| EP-3319946-A1 | SIMPLIFIED AND SCALABLE METHOD FOR SYNTHESIS OF 2,6-BIS(METHIONYL)-1,4-DIKETOPIPERAZINE | Evonik Degussa GmbH (DE) | 2018-05-16 | — | — | EP | disclosed |
| WO-2017005547-A1 | SIMPLIFIED AND SCALABLE METHOD FOR SYNTHESIS OF 2,6-BIS(METHIONYL)-1,4-DIKETOPIPERAZINE | EVONIK DEGUSSA GMBH (DE) | 2017-01-12 | — | — | WO | disclosed |
| EP-2348881-B1 | PRODUCTION AND USE OF METHIONYL-METHIONINE AS A FEED ADDITIVE FOR FISH AND CRUSTACEANS | EVONIK DEGUSSA GMBH (DE) | 2013-09-04 | — | — | EP | disclosed |
| US-4423175-A | AND ALKALINE EARTH, ZINC, OR TIN COMPOUND | AJINOMOTO COMPANY INCORPORATED (JP) | 1983-12-27 | — | — | US | disclosed |
| US-4384059-A | ADDITIONALLY WITH ALKALINE EARTH METAL, ZINC AND ORGANO TIN COMPOUNDS | AJINOMOTO COMPANY INCORPORATED (JP) | 1983-05-17 | — | — | US | disclosed |
| US-3980653-A | Process for the production of 3,6-bis-(2-methylmercaptoethyl)-2,5-piperazinedione | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-09-14 | — | — | US | disclosed |
| US-3980653-A | Process for the production of 3,6-bis-(2-methylmercaptoethyl)-2,5-piperazinedione | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-09-14 | — | — | US | disclosed |
| US-3980653-A | Process for the production of 3,6-bis-(2-methylmercaptoethyl)-2,5-piperazinedione | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194804-A1 | SIMPLIFIED AND SCALABLE METHOD FOR SYNTHESIS OF 2,6-BIS(METHIONYL)- 1,4-DIKETOPIPERAZINE | METAP2, MTX2, METTL3 | KDM4E 666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.