SCHEMBL11174102

SCHEMBL11174102

Cc1[nH]c2ccccc2c1N=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AHR P35869 1/20 0.55
▸ MAPT P10636 11/20 0.54
▸ MEN1 O00255 8/20 0.54
▸ KMT2A Q03164 8/20 0.54
▸ GAA P10253 4/20 0.54
▸ SMN1; SMN2 Q16637 3/20 0.54
▸ NPSR1 Q6W5P4 2/20 0.54
▸ ALDH1A1 P00352 5/20 0.53
▸ CCNB2 O95067 3/20 0.53
▸ CDK1 P06493 3/20 0.53
▸ CCNB1 P14635 3/20 0.53
▸ CCNB3 Q8WWL7 3/20 0.53
▸ NPC1 O15118 2/20 0.53
▸ MAPK1 P28482 2/20 0.53
▸ RAB9A P51151 2/20 0.53
▸ LMNA P02545 2/20 0.53
▸ HTT P42858 2/20 0.53
▸ CYP3A4 P08684 2/20 0.53
▸ GSK3A P49840 2/20 0.53
▸ GSK3B P49841 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29924508 0.76 GSK3B (0.72) MAPTMEN1KMT2ASMN1; SMN2NPSR1
SCHEMBL7905132 0.76 MAPT (0.77) AHRMAPTMEN1KMT2AGAA
SCHEMBL7905135 0.76 MAPT (0.77) AHRMAPTMEN1KMT2AGAA
SCHEMBL19385386 0.76 MAPT (0.50) AHRMAPTMEN1KMT2AGAA
SCHEMBL4064946 0.74 CDK5 (0.60) AHRMAPTMEN1KMT2ASMN1; SMN2
SCHEMBL13098044 0.74 GRIN2D (0.56) MAPTMEN1KMT2AGAASMN1; SMN2
SCHEMBL23135871 0.73 MAPT (0.48) AHRMAPTMEN1KMT2AGAA
SCHEMBL21420157 0.73 MAPT (0.77) AHRMAPTMEN1KMT2AGAA
SCHEMBL29420757 0.72 AHR (1.00) AHRMAPTMEN1KMT2AGAA
SCHEMBL154593 0.72 AHR (1.00) AHRMAPTMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 — — US claimed
US-4314058-A Indolins styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-02-02 — — US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 — — US claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 — — US disclosed
US-4314058-A Indolins styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-02-02 — — US disclosed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 — — US disclosed
US-4139274-A Apparatus for changing color MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-02-13 — — US disclosed
US-4003633-A Color display device MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-01-18 — — US disclosed
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