Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28882768 | 0.79 | ALDH1A1 (0.40) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL19400880 | 0.77 | ESR1 (0.50) | MAPTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL11174102 | 0.76 | AHR (0.55) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL28245664 | 0.75 | KIF11 (0.39) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL19385398 | 0.73 | KDM4E (0.51) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL19385394 | 0.73 | KDM4E (0.51) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL19385396 | 0.73 | GAA (0.62) | MAPTGAAALDH1A1HPGDTSHR | |
| SCHEMBL7905132 | 0.71 | MAPT (0.77) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL7905135 | 0.71 | MAPT (0.77) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL29789603 | 0.70 | KIF11 (0.49) | MAPTMEN1KMT2ANPSR1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017163263-A1 | INDOLE DERIVATIVES, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | claimed |
| WO-2017163263-A1 | INDOLE DERIVATIVES, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | disclosed |
| WO-2017163263-A1 | INDOLE DERIVATIVES, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | disclosed |