Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.77 |
| ▸ | MEN1 | O00255 | 11/20 | 0.77 |
| ▸ | GAA | P10253 | 5/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.60 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | IDO1 | P14902 | 3/20 | 0.53 |
| ▸ | TDO2 | P48775 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905135 | 0.90 | MAPT (0.77) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL7905132 | 0.90 | MAPT (0.77) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL29284806 | 0.84 | KMT2A (0.57) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL30950638 | 0.84 | KMT2A (0.57) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL13208885 | 0.76 | MAPT (0.58) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL16588399 | 0.75 | MAPT (0.57) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL11174102 | 0.73 | AHR (0.55) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL18463682 | 0.71 | IDO1 (0.71) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL17179364 | 0.70 | PTGS2 (0.55) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL23483898 | 0.69 | KMT2A (1.00) | MAPTKMT2AMEN1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190300480-A1 | BINDING FUNCTION 3 (BF3) SITE COMPOUNDS AS THERAPEUTICS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2019-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190300480-A1 | BINDING FUNCTION 3 (BF3) SITE COMPOUNDS AS THERAPEUTICS AND METHODS FOR THEIR USE | KLK3, SHBG, ACP3 | MAPT 3442/4885KMT2A 4323/4885MEN1 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.