Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463737 | 0.90 | ALDH1A1 (0.39) | MAPTGAATP53MAPK1HSD17B10 | |
| SCHEMBL17006480 | 0.85 | HTT (0.57) | MAPTALDH1A1KMT2AHPGDLMNA | |
| SCHEMBL10601266 | 0.82 | MAPT (0.47) | MAPTGAATP53MAPK1HSD17B10 | |
| SCHEMBL11171569 | 0.81 | MAPT (0.46) | MAPTGAATP53MAPK1HSD17B10 | |
| SCHEMBL11169978 | 0.80 | MAPT (0.45) | MAPTGAATP53MAPK1HSD17B10 | |
| SCHEMBL28876712 | 0.80 | IDO1 (0.44) | MAPTTP53ALDH1A1LMNAHTT | |
| SCHEMBL10392041 | 0.79 | ALDH1A1 (0.39) | MAPTMAPK1CYP2C9ALDH1A1KMT2A | |
| SCHEMBL11038064 | 0.78 | MAPT (0.57) | MAPTGAATP53MAPK1HSD17B10 | |
| SCHEMBL11169745 | 0.77 | MAPT (0.43) | MAPTGAATP53MAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL10392835 | 0.77 | ALDH1A1 (0.39) | MAPTGAAMAPK1CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4369325-A | ANTIPHLOGISTIC AND DIURETIC ACTIVITY | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1983-01-18 | — | — | US | disclosed |
| US-4284642-A | DIURETICS, ANTIPHLOGISTICS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1981-08-18 | — | — | US | disclosed |