Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10392835 | 0.98 | ALDH1A1 (0.39) | ALDH1A1KDM4ECYP1A2MEN1CYP2C9 | |
| SCHEMBL11174062 | 0.87 | GAA (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2ADRB2 | |
| SCHEMBL27754049 | 0.86 | PTGS2 (0.46) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27950619 | 0.83 | MAPT (0.41) | ALDH1A1KDM4ECYP1A2MEN1CYP2C9 | |
| SCHEMBL10391083 | 0.81 | ATM (0.38) | ALDH1A1CYP1A2MEN1CYP2C9NFKB1 | |
| SCHEMBL11177788 | 0.79 | RAPGEF4 (0.44) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPK1 | |
| SCHEMBL11169204 | 0.79 | MAPT (0.34) | ALDH1A1CYP1A2MEN1CYP2C9NFKB1 | |
| SCHEMBL10391707 | 0.79 | SCN4A (0.46) | CYP1A2CYP2C9NFKB1LMNACYP2D6 | |
| SCHEMBL11363761 | 0.79 | TSHR (0.47) | CYP1A2MEN1CYP2C9NFKB1CYP2C19 | |
| SCHEMBL11174233 | 0.79 | MAPT (0.50) | ALDH1A1CYP1A2MEN1CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4922021-A | ANTIARRHYTHMIA AGENTS | BASF AKTIENSELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| US-4412855-A | 2-Chloro-N-(2'-methoxypropyl)- and 2-chloro-N-(2'-ethoxypropyl)-2\",6\"-dimethyl-acetanilide as long term weed killers | CIBA-GEIGY CORPORATION (US) | 1983-11-01 | — | — | US | disclosed |
| US-4369325-A | ANTIPHLOGISTIC AND DIURETIC ACTIVITY | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1983-01-18 | — | — | US | disclosed |
| US-4284642-A | DIURETICS, ANTIPHLOGISTICS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1981-08-18 | — | — | US | disclosed |