Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL11162985 | 0.82 | L3MBTL1 (0.55) | MAPTALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL6154940 | 0.80 | ALDH1A1 (0.58) | KMT2AMAPTALDH1A1GAAHTT | |
| Iodide SCHEMBL11164966 | 0.77 | NPC1 (0.52) | KMT2AMAPTALDH1A1HTTPOLB | |
| SCHEMBL8029769 | 0.77 | MAPT (0.59) | KMT2AMAPTALDH1A1GAAHTT | |
| Iodide SCHEMBL11164129 | 0.75 | LMNA (0.44) | KMT2AMAPTALDH1A1GAAPOLB | |
| Iodide SCHEMBL11167173 | 0.75 | HTT (0.47) | KMT2AMAPTGAAHTTLMNA | |
| SCHEMBL28283706 | 0.75 | MAPT (0.53) | KMT2AMAPTALDH1A1GAAHTT | |
| SCHEMBL14122825 | 0.74 | ALDH1A1 (0.51) | KMT2AMAPTALDH1A1GAAHTT | |
| SCHEMBL27935930 | 0.74 | MAPT (0.54) | KMT2AMAPTALDH1A1GAAHTT | |
| Iodide SCHEMBL1286920 | 0.74 | KDM4E (0.53) | KMT2AMAPTALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4414211-A | HYPOGLYCEMIC/- | MCNEILAB, INC. (US) | 1983-11-08 | — | — | US | disclosed |