Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CETP | P11597 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | UBE2N | P61088 | 1/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.54 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16390229 | 1.00 | CYP2D6 (0.59) | CYP2D6LMNASPHK1TP53GMNN | |
| SCHEMBL16390346 | 1.00 | CYP2D6 (0.59) | CYP2D6LMNASPHK1TP53GMNN | |
| SCHEMBL16390173 | 1.00 | CYP2D6 (0.59) | CYP2D6LMNASPHK1TP53GMNN | |
| SCHEMBL1117440 | 1.00 | CYP2D6 (0.59) | CYP2D6LMNASPHK1TP53GMNN | |
| SCHEMBL16390457 | 1.00 | CYP2D6 (0.59) | CYP2D6LMNASPHK1TP53GMNN | |
| SCHEMBL21660301 | 1.00 | CYP2D6 (0.59) | CYP2D6LMNASPHK1TP53GMNN | |
| SCHEMBL16390061 | 1.00 | CYP2D6 (0.59) | CYP2D6LMNASPHK1TP53GMNN | |
| SCHEMBL16071037 | 1.00 | CYP2D6 (0.59) | CYP2D6LMNASPHK1TP53GMNN | |
| SCHEMBL1117453 | 1.00 | CYP2D6 (0.59) | CYP2D6LMNASPHK1TP53GMNN | |
| SCHEMBL16390540 | 1.00 | CYP2D6 (0.59) | CYP2D6LMNASPHK1TP53GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3121162-A1 | NITRATED HYDROCARBONS AND DERIVATIVES | ANGUS CHEMICAL COMPANY (US) | 2017-01-25 | — | — | EP | claimed |
| US-20160039843-A1 | NITRATED HYDROCARBONS, DERIVATIVES, AND PROCESSES FOR THEIR MANUFACTURE | ADVANCION CORPORATION | 2016-02-11 | — | — | US | claimed |
| CN-101998948-A | Nitrated hydrocarbons, derivatives and processes for their manufacture | DOW GLOBAL TECHNOLOGIES INCANGUS CHEMICAL COMPANY | 2011-03-30 | — | — | CN | claimed |
| EP-2280927-A1 | NITRATED HYDROCARBONS, DERIVATIVES, AND PROCESSES FOR THEIR MANUFACTURE | ANGUS CHEMICAL COMPANY (US) | 2011-02-09 | — | — | EP | claimed |
| US-20110028732-A1 | NITRATED HYDROCARBONS, DERIVATIVES, AND PROCESSES FOR THEIR MANUFACTURE | ANGUS CHEMICAL COMPANY (US) | 2011-02-03 | — | — | US | claimed |
| WO-2009129097-A1 | NITRATED HYDROCARBONS, DERIVATIVES, AND PROCESSES FOR THEIR MANUFACTURE | ANGUS CHEMICAL COMPANY (US) | 2009-10-22 | — | — | WO | claimed |
| US-11542277-B2 | Nitrated hydrocarbons, derivatives, and processes for their manufacture | ANGUS CHEMICAL COMPANY (US) | 2023-01-03 | — | — | US | disclosed |
| EP-3121162-B1 | PROCESS FOR PREPARING NITRATED HYDROCARBONS AND THEIR DERIVATIVES | ANGUS CHEMICAL (US) | 2021-05-26 | — | — | EP | disclosed |
| US-10662397-B2 | Aqueous formulations, their manufacture, and their use in hard surface cleaning | BASF SE (DE) | 2020-05-26 | — | — | US | disclosed |
| EP-3188733-B1 | CONJUGATES COMPRISING CELL-BINDING AGENTS AND CYTOTOXIC AGENTS | IMMUNOGEN INC (US) | 2019-11-06 | — | — | EP | disclosed |
| US-20190315768-A1 | NITRATED HYDROCARBONS, DERIVATIVES, AND PROCESSES FOR THEIR MANUFACTURE | ADVANCION CORPORATION | 2019-10-17 | — | — | US | disclosed |
| US-10377771-B2 | Nitrated hydrocarbons, derivatives, and processes for their manufacture | ANGUS CHEMICAL COMPANY (US) | 2019-08-13 | — | — | US | disclosed |
| US-10301576-B2 | Formulations, their use as or for producing dishwashing detergents and their production | BASF SE (DE) | 2019-05-28 | — | — | US | disclosed |
| CN-1136848-C | Application of bilirubin bitaurine sodium and its bilirubin derivative in preparing anti-HIV medicine | 中国科学院化学研究所 | 2004-02-04 | — | — | CN | disclosed |
| CN-1315176-A | Application of bilirubin bitaurine sodium and its bilirubin derivative in preparing anti-HIV medicine | INST PHOTOSENSITIVE CHEMISTRY CAS (CN) | 2001-10-03 | — | — | CN | disclosed |
| EP-0404146-B1 | Enantiomeric enrichment and stereoselective synthesis of chiral amines | CELGENE CORP (US) | 1996-03-20 | — | — | EP | disclosed |
| US-5300437-A | Using omega-amino acid transaminase | CELGENE CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| US-5169780-A | Conversion to ketone in aqueous solution with amino acceptor and omega-amino acid acceptor; solvent extraction | CELGENE CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0404146-A2 | Enantiomeric enrichment and stereoselective synthesis of chiral amines | CELGENE CORPORATION (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4950606-A | CONTACTING IN AN AQUEOUS MEDIUM IN THE PRESENCE OF AN AMINO ACCEPTOR WITH AN OMEGA-AMINO ACID TRANSAMINASE TO CONVERT ONE OF AMINES TO KETONE | CELGENE CORPORATION (US) | 1990-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11542277-B2 | Nitrated hydrocarbons, derivatives, and processes for their manufacture | NOS2, NOS1, NOS3 | CYP2D6 232/4885LMNA 1670/4885SPHK1 1996/4885 |
| US-20190315768-A1 | NITRATED HYDROCARBONS, DERIVATIVES, AND PROCESSES FOR THEIR MANUFACTURE | NOS2, NOS1, NOS3 | CYP2D6 232/4885LMNA 1670/4885SPHK1 1996/4885 |
| US-20110028732-A1 | NITRATED HYDROCARBONS, DERIVATIVES, AND PROCESSES FOR THEIR MANUFACTURE | NOS2, NOS1, NOS3 | CYP2D6 232/4885LMNA 1670/4885SPHK1 1996/4885 |
| US-20160039843-A1 | NITRATED HYDROCARBONS, DERIVATIVES, AND PROCESSES FOR THEIR MANUFACTURE | NOS2, NOS1, NOS3 | CYP2D6 232/4885LMNA 1670/4885SPHK1 1996/4885 |
| US-10377771-B2 | Nitrated hydrocarbons, derivatives, and processes for their manufacture | NOS2, NOS1, NOS3 | CYP2D6 232/4885LMNA 1670/4885SPHK1 1996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.