Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.38 |
| ▸ | TUBB | P07437 | 2/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11167292 | 0.91 | CYP11B1 (0.46) | CYP11B1CYP11B2MTNR1AMTNR1BPARP1 | |
| SCHEMBL11164908 | 0.86 | CYP11B1 (0.45) | CYP11B1CYP11B2MTNR1AMTNR1BPARP1 | |
| SCHEMBL5146760 | 0.82 | TBXAS1 (0.47) | CYP11B1CYP11B2PARP1 | |
| SCHEMBL11167375 | 0.82 | TBXAS1 (0.47) | CYP11B1CYP11B2PARP1 | |
| SCHEMBL11174681 | 0.82 | CYP11B1 (0.51) | CYP11B1CYP11B2MTNR1AMTNR1BPARP1 | |
| SCHEMBL11167802 | 0.82 | CYP11B1 (0.45) | CYP11B1CYP11B2MTNR1APARP1HDAC1 | |
| SCHEMBL11172992 | 0.81 | CYP11B1 (0.48) | CYP11B1CYP11B2PARP1TUBB4ATUBB | |
| SCHEMBL11164579 | 0.81 | CYP11B1 (0.52) | CYP11B1CYP11B2PARP1TUBB4ATUBB | |
| SCHEMBL11175985 | 0.79 | CYP11B1 (0.48) | CYP11B1CYP11B2MTNR1AMTNR1BPARP1 | |
| SCHEMBL11162993 | 0.79 | CYP11B1 (0.43) | CYP11B1CYP11B2PARP1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080154-A2 | N-substituted 2-pyridyl indoles, process for their preparation, pharmaceutical compositions containing them, and their therapeutical use | CIBA-GEIGY AG (CH) | 1983-06-01 | — | — | EP | disclosed |