SCHEMBL11178696

SCHEMBL11178696

CN(C)C(=O)CCn1[c]n[nH]c(=O)c1=O

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11174588 0.84 NPSR1 (0.35) GAARXFP1NPSR1ALDH1A1
SCHEMBL11175530 0.80 PDE4A (0.33)
SCHEMBL11164951 0.78 CHRNB2 (0.33)
SCHEMBL11171629 0.76 DRD2 (0.33)
SCHEMBL10916747 0.75 PDE4A (0.32)
SCHEMBL11181614 0.75 TERT (0.35) ALDH1A1
SCHEMBL11350396 0.72
SCHEMBL11174294 0.72 CCNE2 (0.34)
SCHEMBL11352571 0.71
SCHEMBL11186130 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4385181-A CHAMICAL INTERMEDIATES FOR CEPHALOSPORINS RHONE POULENC INDUSTRIES (FR) 1983-05-24 US disclosed
US-4307116-A BACTERICIDES RHONE-POULENC INDUSTRIES (FR) 1981-12-22 US disclosed