Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11184423 | 0.90 | KMT2A (0.68) | KMT2AALDH1A1TSHRGAANPBWR1 | |
| SCHEMBL11180002 | 0.89 | TSHR (0.73) | KMT2AALDH1A1TSHRGAANPBWR1 | |
| SCHEMBL11173796 | 0.87 | ALDH1A1 (0.68) | KMT2AALDH1A1TSHRGAAMEN1 | |
| SCHEMBL11167261 | 0.86 | TSHR (0.63) | KMT2AALDH1A1TSHRGAANPBWR1 | |
| SCHEMBL11175056 | 0.82 | KMT2A (0.71) | KMT2AALDH1A1TSHRGAANPBWR1 | |
| SCHEMBL5506579 | 0.81 | KDM4E (0.58) | KMT2AALDH1A1TSHRGAANPBWR1 | |
| SCHEMBL1001171 | 0.80 | RAB9A (0.72) | KMT2AALDH1A1TSHRGAANPBWR1 | |
| SCHEMBL7661191 | 0.80 | RAB9A (0.72) | KMT2AALDH1A1TSHRGAANPBWR1 | |
| SCHEMBL7661631 | 0.78 | RAB9A (0.73) | KMT2AALDH1A1TSHRGAAMEN1 | |
| SCHEMBL11172100 | 0.77 | TSHR (0.52) | KMT2AALDH1A1TSHRGAANPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4377521-A | ANTILIPEMIC | PFIZER INC. (US) | 1983-03-22 | — | — | US | disclosed |
| US-4138399-A | Sulfamylbenzoic acid | PFIZER INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4124590-A | CARDIOVASCULAR DISORDERS, ANTILIPEMIC AGENTS | PFIZER INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-3992441-A | ANTILIPEMIC | PFIZER INC. (US) | 1976-11-16 | — | — | US | disclosed |