Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PDE1A | P54750 | 2/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11185140 | 0.84 | HSD17B10 (0.39) | ALDH1A1KDM4ELMNAPDE1AMEN1 | |
| SCHEMBL11190156 | 0.82 | HSD17B10 (0.35) | ALDH1A1KDM4ELMNAMAPTPDE1A | |
| SCHEMBL11184331 | 0.81 | CNR2 (0.36) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL11190506 | 0.80 | ALDH1A1 (0.37) | ALDH1A1KDM4ERAB9ALMNAMEN1 | |
| SCHEMBL11185552 | 0.78 | HPGD (0.38) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL11177134 | 0.77 | TSHR (0.41) | ALDH1A1KDM4EL3MBTL1RAB9ALMNA | |
| SCHEMBL11190030 | 0.77 | PDE1A (0.40) | ALDH1A1KDM4EL3MBTL1RAB9ALMNA | |
| SCHEMBL11187623 | 0.76 | HSD17B10 (0.41) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL11187463 | 0.73 | HSD17B10 (0.39) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL11206732 | 0.69 | MEN1 (0.38) | ALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4367230-A | ANTIANOXIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1983-01-04 | — | — | US | disclosed |