Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11190506 | 0.84 | ALDH1A1 (0.37) | CNR2ALDH1A1KDM4EBRD4LMNA | |
| SCHEMBL11178985 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNACHRM2ADRA2B | |
| SCHEMBL11185140 | 0.81 | HSD17B10 (0.39) | ALDH1A1KDM4EBRD4LMNAHTR2A | |
| SCHEMBL11190156 | 0.81 | HSD17B10 (0.35) | ALDH1A1KDM4EBRD4LMNACHRM2 | |
| SCHEMBL11180821 | 0.78 | AKR1B10 (0.36) | CNR2OPRM1OPRL1LMNA | |
| SCHEMBL11187623 | 0.77 | HSD17B10 (0.41) | ALDH1A1KDM4EBRD4LMNACREBBP | |
| SCHEMBL11185552 | 0.77 | HPGD (0.38) | ALDH1A1KDM4ERENHTR2AMEN1 | |
| SCHEMBL11187463 | 0.72 | HSD17B10 (0.39) | ALDH1A1KDM4ELMNACREBBPHTR2A | |
| SCHEMBL11195470 | 0.70 | KDM4E (0.39) | CNR2ALDH1A1KDM4ECNR1LMNA | |
| SCHEMBL11206732 | 0.68 | MEN1 (0.38) | ALDH1A1MEN1HPGDKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4367230-A | ANTIANOXIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1983-01-04 | — | — | US | disclosed |