Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11181436 | 1.00 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2NPSR1HPGDTAS1R3 | |
| SCHEMBL11186564 | 0.85 | LMNA (0.49) | ALDH1A1SMN1; SMN2HPGDTAS1R3TAS1R1 | |
| SCHEMBL11186560 | 0.85 | LMNA (0.49) | ALDH1A1SMN1; SMN2HPGDTAS1R3TAS1R1 | |
| SCHEMBL11188856 | 0.77 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2NPSR1MAPTHCAR2 | |
| SCHEMBL11188848 | 0.77 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2NPSR1MAPTHCAR2 | |
| Hydrochloric Acid SCHEMBL11188573 | 0.76 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2NPSR1HPGDTAS1R3 | |
| Hydrochloric Acid SCHEMBL11188582 | 0.76 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2NPSR1HPGDTAS1R3 | |
| SCHEMBL11181441 | 0.76 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2HPGDTAS1R3TAS1R1 | |
| SCHEMBL11188209 | 0.74 | HCAR2 (0.49) | ALDH1A1SMN1; SMN2HPGDKDM4EMAPT | |
| SCHEMBL11188205 | 0.74 | HCAR2 (0.49) | ALDH1A1SMN1; SMN2HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4407816-A | ANTIULCER | KOTOBUKI SEIYAKU COMPANY LIMITED (JP) | 1983-10-04 | — | — | US | disclosed |