Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11188209 | 1.00 | HCAR2 (0.49) | HCAR2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL11760027 | 0.80 | HCAR2 (0.55) | HCAR2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL11186560 | 0.77 | LMNA (0.49) | HCAR2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL11227559 | 0.75 | HCAR2 (0.58) | HCAR2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL11181440 | 0.74 | ALDH1A1 (0.45) | HCAR2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL11181436 | 0.74 | ALDH1A1 (0.45) | HCAR2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL1086015 | 0.73 | HCAR2 (0.71) | HCAR2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL4197243 | 0.73 | HCAR2 (0.71) | HCAR2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27931367 | 0.72 | HCAR2 (0.69) | HCAR2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL27843842 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4407816-A | ANTIULCER | KOTOBUKI SEIYAKU COMPANY LIMITED (JP) | 1983-10-04 | — | — | US | disclosed |