Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.52 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MC3R | P41968 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | PTGFR | P43088 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13211811 | 0.84 | KDM4E (0.41) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL13105834 | 0.84 | KDM4E (0.41) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL11912325 | 0.84 | KDM4E (0.41) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL10702946 | 0.84 | KDM4E (0.41) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL13119881 | 0.84 | KDM4E (0.41) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL12363806 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL12363820 | 0.80 | PGR (0.38) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL7671826 | 0.80 | KDM4E (0.38) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL7671832 | 0.80 | KDM4E (0.38) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL7671839 | 0.80 | KDM4E (0.38) | ALDH1A1KDM4EHKDC1TDP1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4378370-A | Certain 5-cyano-16-fluoro-prostacyclins and their use as pharmaceuticals | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-03-29 | — | — | US | disclosed |