Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11187742 | 0.92 | CNR1 (0.49) | KDM4EALDH1A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL11185202 | 0.90 | KDM4E (0.53) | KDM4EALDH1A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL11182289 | 0.87 | KDM4E (0.56) | KDM4EALDH1A1TP53SMN1; SMN2TSHR | |
| SCHEMBL11193299 | 0.86 | KDM4E (0.55) | KDM4EALDH1A1TP53MAPTSMN1; SMN2 | |
| Maleic Acid SCHEMBL11184890 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1TP53MAPTSMN1; SMN2 | |
| Fumaric Acid SCHEMBL11184896 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL11186543 | 0.83 | ALDH1A1 (0.54) | KDM4EALDH1A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL11190927 | 0.82 | TSHR (0.49) | KDM4EALDH1A1MAPTCNR1TSHR | |
| SCHEMBL11183958 | 0.82 | KDR (0.53) | KDM4EMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL3028528 | 0.81 | KDM4E (0.55) | KDM4EALDH1A1TP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4420619-A | Imidazole urea and amido compounds | CIBA-GEIGY CORPORATION (US) | 1983-12-13 | — | — | US | disclosed |
| US-4292429-A | Imidazole urea and amido compounds | CIBA-GEIGY CORPORATION (US) | 1981-09-29 | — | — | US | disclosed |