Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274238 | 0.85 | ALDH1A1 (0.55) | AGTR1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL6203064 | 0.75 | ALDH1A1 (0.56) | AGTR1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL11123393 | 0.75 | RXFP1 (0.59) | MEN1KMT2AALDH1A1RAB9AHTT | |
| SCHEMBL23014348 | 0.74 | HPGD (0.59) | AGTR1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL2295610 | 0.73 | GSK3B (0.57) | AGTR1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL2582559 | 0.73 | PTGS2 (0.49) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL15524678 | 0.73 | MEN1 (0.50) | MEN1KMT2AALDH1A1RAB9AHTT | |
| SCHEMBL14830961 | 0.72 | ERCC5 (0.58) | AGTR1MEN1KMT2AALDH1A1RAB9A | |
| Bromide SCHEMBL2582738 | 0.72 | PTGS2 (0.47) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL11273478 | 0.72 | DRD2 (0.46) | MEN1KMT2AALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4422866-A | N,N'-DISUBSTITUTED PIPERAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | disclosed |
| US-4392882-A | N-N-Bis(haloacyl)-diaza-cycloalkanes for protecting plants from herbicide damage | BAYER AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | disclosed |
| US-4312664-A | N,N-DIALLYL-DICHLOROACETAMIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-26 | — | — | US | disclosed |
| EP-0023306-A1 | N-(Alpha-chloropropionyl)-1,2,3,4-tetrahydro-quinaldine, process for its preparation and its use as antidote in preventing damage to crops by herbicides | BAYER AG (DE) | 1981-02-04 | — | — | EP | disclosed |
| EP-0023305-A1 | Use of N,N'-bis(halogen-acyl)-diaza-cycloalkanes for the protection of cultivated plants against damage by herbicides | BAYER AG (DE) | 1981-02-04 | — | — | EP | disclosed |
| EP-0023307-A1 | N-(alpha-chloropropionyl)-1,2,3,4-tetrahydroisoquinoline, process for its preparation and its use as antidote in the protection of crop plants against damage by herbicides | BAYER AG (DE) | 1981-02-04 | — | — | EP | disclosed |
| EP-0023287-A1 | Antidote for the protection of cultivated plants against damage by herbicides | BAYER AG (DE) | 1981-02-04 | — | — | EP | disclosed |
| EP-0000051-B1 | N-ACYLMETHYL-CHLOROACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES. | BAYER AG (DE) | 1980-09-17 | — | — | EP | disclosed |
| EP-0006541-A2 | Use of N,N-diallyl-dichloroacetamide for improving the protection of crop plants against herbicidally active acetanilides | BAYER AG (DE) | 1980-01-09 | — | — | EP | disclosed |
| EP-0006542-A2 | The use of N-dichloroacetyl-1,2,3,4-tetrahydroisoquinolin as antidote for the protection of cultivated plants against damage caused by herbicidally active acetanilides; combinations thus obtained and process for their preparation | BAYER AG (DE) | 1980-01-09 | — | — | EP | disclosed |
| EP-0006540-A1 | N-Dichloroacetyl-1,2,3,4-tetrahydroquinaldine, process for obtaining it, its use for preventing crops from being damaged by herbicides and selective herbicidal compositions based on N-dichloroacetyl-1,2,3,4-tetrahydroquinaldine and herbicidal acetanilides or thiolcarbamates | BAYER AG (DE) | 1980-01-09 | — | — | EP | disclosed |
| EP-0000051-A1 | N-acylmethyl-chloroacetanilides, process for their preparation and their use as herbicides. | BAYER AG (DE) | 1978-12-20 | — | — | EP | disclosed |