SCHEMBL1118436

SCHEMBL1118436

COc1cc(NC(=O)CC(C)=O)c(OC)cc1Cl

nearest known ligand 0.88

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.73
ALDH1A1 P00352 6/20 0.67
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67
MAPT P10636 2/20 0.58
NPSR1 Q6W5P4 3/20 0.57
TSHR P16473 2/20 0.57
LMNA P02545 2/20 0.57
KDM4E B2RXH2 2/20 0.57
TP53 P04637 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
GAA P10253 1/20 0.55
HPGD P15428 1/20 0.55
HTT P42858 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466463 1.00 SMN1; SMN2 (0.73) SMN1; SMN2ALDH1A1MEN1KMT2AMAPT
SCHEMBL7130005 0.94 ALDH1A1 (0.73) SMN1; SMN2ALDH1A1MEN1KMT2AMAPT
SCHEMBL31570092 0.94 ALDH1A1 (0.73) SMN1; SMN2ALDH1A1MEN1KMT2AMAPT
SCHEMBL11576993 0.92 ALDH1A1 (0.68) SMN1; SMN2ALDH1A1MEN1KMT2AMAPT
SCHEMBL2914320 0.91 ALDH1A1 (0.67) SMN1; SMN2ALDH1A1MEN1KMT2AMAPT
SCHEMBL2914361 0.90 ALDH1A1 (0.69) SMN1; SMN2ALDH1A1MEN1KMT2AMAPT
SCHEMBL11576267 0.88 ALDH1A1 (0.65) SMN1; SMN2ALDH1A1MEN1KMT2AMAPT
SCHEMBL11575484 0.87 ALDH1A1 (0.62) SMN1; SMN2ALDH1A1MEN1KMT2AMAPT
SCHEMBL24499459 0.84 SMN1; SMN2 (0.73) SMN1; SMN2ALDH1A1MAPTNPSR1TSHR
SCHEMBL27896148 0.84 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022228846-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-11-03 WO claimed
WO-2022117389-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-06-09 WO claimed
EP-3561003-A1 A HYBRID PIGMENT, METHOD FOR PREPARATION THEREOF AND USES THEREOF Clariant Plastics & Coatings Ltd (CH) 2019-10-30 EP claimed
EP-1169393-B1 ACETOACETYLARYLIDE SUSPENSIONS IN PIGMENT APPLICATIONS LONZA AG (CH) 2008-06-11 EP claimed
EP-1169393-A1 ACETOACETYLARYLIDE SUSPENSIONS IN PIGMENT APPLICATIONS Lonza AG (CH) 2002-01-09 EP claimed
WO-2000061688-A1 ACETOACETYLARYLIDE SUSPENSIONS IN PIGMENT APPLICATIONS LONZA AG (CH) 2000-10-19 WO claimed
US-6099635-A HOMOGENIZING THE MIXTURE OF ACETOACETARYLIDE WITH ONE OR MORE ADDITIVES TO FORM A SLURRY OF THE ACETOACETARYLIDE LONZA AG (CH) 2000-08-08 US claimed
US-5958128-A CONTINUOUSLY FEEDING AN ACETOACETANILIDE DERIVATIVE AS A COUPLER AND A TETRAAZO BENZIDINE DERIVATIVE INTO AN ACIDIC AQUEOUS SOLUTION TO FORM DISAZO PIGMENT TOYO INK MANUFACTURING CO., LTD. (JP) 1999-09-28 US claimed
EP-0826742-A1 PROCESS FOR THE PREPARATION OF DISAZO PIGMENTS AND DISAZO PIGMENTS PREPARED BY THE PROCESS TOYO INK MANUFACTURING CO., LTD. (JP) 1998-03-04 EP claimed
EP-0587021-B1 Use of preparations of azo-pigments containing solvents for intaglio printing and flexographic printing on packaging HOECHST AG (DE) 1995-08-16 EP claimed
EP-0263951-A2 Disazo compounds and compositions containing them BASF Lacke + Farben AG (DE) 1988-04-20 EP claimed
US-4665163-A YELLOW SHADES IN PLASTICS HOECHST AKTIENGESELLSCHAFT (DE) 1987-05-12 US claimed
EP-0097912-B1 Use of diaryl pigments for the pigmentation of plastics HOECHST AKTIENGESELLSCHAFT (DE) 1987-01-14 EP claimed
US-4602960-A Modified diarylide pigments and their preparation BASF FARBEN & FASERN AKTIENGESELLSCHAFT (DE) 1986-07-29 US claimed
EP-0053713-B1 PROCESS FOR PREPARING 1-ACETYLAMINO-4-CHLORO-2,5 DIMETHOXYBENZENE HOECHST AKTIENGESELLSCHAFT (DE) 1984-07-04 EP claimed
EP-0097912-A1 Use of diaryl pigments for the pigmentation of plastics HOECHST AKTIENGESELLSCHAFT (DE) 1984-01-11 EP claimed
EP-0053713-A1 Process for preparing 1-acetylamino-4-chloro-2,5 dimethoxybenzene HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-16 EP claimed
US-4169851-A PROCESS FOR THE MANUFACTURE OF ACETOACETYL-AMINOBENZENES HOECHST AKTIENGESELLSCHAFT (DE) 1979-10-02 US claimed
EP-0001994-A1 Process for preparing acetylaminobenzenes HOECHST AKTIENGESELLSCHAFT (DE) 1979-05-30 EP claimed
US-4042622-A Process for the preparation of N-acetoacetyl-2,5-dimethoxy-4-chloroanilide HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-16 US claimed