Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914320 | 0.96 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL11576993 | 0.88 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL11775480 | 0.88 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL7130005 | 0.87 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL31570092 | 0.87 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL1118436 | 0.87 | SMN1; SMN2 (0.73) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL29466463 | 0.87 | SMN1; SMN2 (0.73) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL2914361 | 0.86 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL2914539 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL10891532 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |