Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187405 | 0.93 | ALDH1A1 (0.32) | EHMT2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11179811 | 0.87 | CYP19A1 (0.40) | MEN1NSD2KMT2APOLBBLM | |
| SCHEMBL4198995 | 0.83 | MEN1 (0.37) | MEN1NSD2KMT2APOLBBLM | |
| SCHEMBL4186617 | 0.79 | ALDH1A1 (0.32) | MEN1NSD2KMT2ABLMALDH1A1 | |
| SCHEMBL4191344 | 0.78 | DRD2 (0.36) | KMT2AALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL4193611 | 0.77 | SLC6A4 (0.38) | MEN1KMT2APOLBKDM4EL3MBTL1 | |
| SCHEMBL11178298 | 0.77 | CYP19A1 (0.44) | MEN1NSD2KMT2APOLBBLM | |
| SCHEMBL4200315 | 0.76 | KDM4E (0.42) | MEN1NSD2KMT2ABLMMAPT | |
| SCHEMBL4191462 | 0.76 | NQO1 (0.38) | MEN1NSD2KMT2APOLBBLM | |
| SCHEMBL11184786 | 0.75 | NQO1 (0.41) | MEN1NSD2KMT2APOLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410524-A | ANTITUMOR AGENTS, LEUREMIA | AMERICAN CYANAMID COMPANY (US) | 1983-10-18 | — | — | US | claimed |