Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11174126 | 0.94 | CYP19A1 (0.40) | DRD2MAPK1L3MBTL1PTGS2DRD3 | |
| SCHEMBL4342591 | 0.90 | MAPK1 (0.35) | DRD2MAPK1L3MBTL1DRD3MAPT | |
| SCHEMBL4186617 | 0.85 | ALDH1A1 (0.32) | MAPK1PTGS2DRD3KMT2AALDH1A1 | |
| SCHEMBL4200315 | 0.85 | KDM4E (0.42) | MAPK1L3MBTL1PTGS2DRD3KMT2A | |
| SCHEMBL4198995 | 0.85 | MEN1 (0.37) | MAPK1L3MBTL1PTGS2DRD3KMT2A | |
| SCHEMBL11175513 | 0.85 | CYP19A1 (0.40) | DRD2MAPK1L3MBTL1PTGS2DRD3 | |
| SCHEMBL4187405 | 0.84 | ALDH1A1 (0.32) | L3MBTL1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL4195625 | 0.84 | MAPK1 (0.43) | MAPK1L3MBTL1KMT2AMAPTALDH1A1 | |
| SCHEMBL11184412 | 0.82 | CYP19A1 (0.41) | DRD2MAPK1L3MBTL1PTGS2DRD3 | |
| SCHEMBL4193611 | 0.81 | SLC6A4 (0.38) | DRD2L3MBTL1DRD3KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD | 2009-06-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | CASP4, CASP8, CASP1 | DRD2 4391/4885MAPK1 802/4885L3MBTL1 1864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.