Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11185651 | 0.82 | ALDH1A1 (0.43) | MAPTSMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL10891764 | 0.80 | MEN1 (0.45) | MAPTSMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL10849346 | 0.77 | ALDH1A1 (0.42) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11214622 | 0.76 | ALDH1A1 (0.41) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6294304 | 0.73 | MEN1 (0.64) | MAPTMEN1KMT2AATMALDH1A1 | |
| SCHEMBL10851145 | 0.70 | GAA (0.45) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL10657219 | 0.68 | ABL1 (0.66) | MAPTSMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL10846141 | 0.68 | NPC1 (0.45) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11057349 | 0.68 | MEN1 (0.54) | MAPTSMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL3283083 | 0.66 | DYRK1A (1.00) | MAPTSMN1; SMN2MEN1KMT2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4376122-A | Novel 3-substituted amino-1-heteroaryl-2-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-03-08 | — | — | US | claimed |
| US-4376122-A | Novel 3-substituted amino-1-heteroaryl-2-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-03-08 | — | — | US | disclosed |
| EP-0070376-A1 | Heterocyclic substituted-amino-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |