Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ATM | Q13315 | 3/20 | 0.45 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890976 | 0.88 | ALDH1A1 (0.43) | MEN1KMT2ASLC27A1HSD17B10ALDH1A1 | |
| SCHEMBL10891545 | 0.86 | ALDH1A1 (0.36) | MEN1KMT2AATMSLC27A1HSD17B10 | |
| SCHEMBL10887197 | 0.85 | MEN1 (0.37) | MEN1KMT2AATMSLC27A1ALDH1A1 | |
| SCHEMBL10892079 | 0.83 | SLC27A1 (0.35) | MEN1KMT2AATMSLC27A1ALDH1A1 | |
| SCHEMBL11185641 | 0.80 | MAPT (0.47) | MEN1KMT2AATMHSD17B10ALDH1A1 | |
| SCHEMBL10894037 | 0.80 | MAPT (0.35) | SLC27A1ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL10890556 | 0.78 | MAPT (0.40) | MEN1KMT2AATMSLC27A1HSD17B10 | |
| SCHEMBL10893914 | 0.72 | ABL1 (0.44) | MEN1KMT2ASLC27A1HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10889776 | 0.71 | ABL1 (0.43) | MEN1KMT2ASLC27A1HSD17B10ALDH1A1 | |
| SCHEMBL10891246 | 0.70 | GAA (0.40) | MEN1KMT2ASLC27A1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600722-A | 3-amino-1-(4,5,6,7-tetrahydro-benzothiazolyl)-2-pyrazolines and a process for the treatment of inflammatory or allergic processes in humans | A. NATTERMANN & CIE GMBH (DE) | 1986-07-15 | — | — | US | disclosed |
| EP-0155523-A1 | 3-Amino-1-(4,5,6,7-Tetrahydro-benzothiazolyl)-2-Pyrazolines,a process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-25 | — | — | EP | disclosed |