Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | CTSG | P08311 | 3/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.44 |
| ▸ | CMA1 | P23946 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683565 | 0.83 | POLB (0.46) | MAPK1KMT2APOLBMEN1ATM | |
| SCHEMBL16097184 | 0.75 | MAPK1 (0.51) | MAPK1KMT2AMMP8POLBMEN1 | |
| SCHEMBL14724517 | 0.74 | RAB9A (0.49) | MAPK1KMT2AMMP8SMN1; SMN2NPC1 | |
| SCHEMBL7220673 | 0.74 | SMN1; SMN2 (0.46) | MAPK1KMT2APOLBMEN1PRSS1 | |
| SCHEMBL27574238 | 0.73 | ALDH1A1 (0.57) | MAPK1KMT2AMMP8POLBMEN1 | |
| SCHEMBL621763 | 0.72 | ALDH1A1 (0.52) | MAPK1KMT2APOLBMEN1ATM | |
| SCHEMBL16097333 | 0.72 | MAPK1 (0.51) | MAPK1KMT2AMMP8POLBMEN1 | |
| SCHEMBL16097699 | 0.71 | MAPK1 (0.50) | MAPK1KMT2APOLBMEN1ATM | |
| SCHEMBL5855427 | 0.71 | MAPK1 (0.47) | MAPK1KMT2APOLBMEN1ATM | |
| SCHEMBL5855413 | 0.71 | MAPK1 (0.47) | MAPK1KMT2APOLBMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |