Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7213700 | 0.77 | GAA (0.45) | GAAL3MBTL1ALDH1A1LMNATSHR | |
| SCHEMBL7221377 | 0.76 | CXCL8 (0.44) | RAB9AALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL10683565 | 0.75 | POLB (0.46) | SMN1; SMN2NPC1GAARAB9APOLB | |
| SCHEMBL11186243 | 0.74 | MAPK1 (0.47) | SMN1; SMN2NPC1GAARAB9APOLB | |
| SCHEMBL27574236 | 0.73 | NPSR1 (0.50) | SMN1; SMN2NPC1GAARAB9AL3MBTL1 | |
| SCHEMBL7220546 | 0.73 | CYP3A4 (0.39) | SMN1; SMN2GAAL3MBTL1ALDH1A1LMNA | |
| SCHEMBL820885 | 0.72 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1GAARAB9AL3MBTL1 | |
| SCHEMBL1221369 | 0.72 | RAB9A (0.66) | SMN1; SMN2NPC1GAARAB9APOLB | |
| SCHEMBL7890971 | 0.72 | L3MBTL1 (0.48) | SMN1; SMN2NPC1GAARAB9AL3MBTL1 | |
| SCHEMBL27553077 | 0.72 | PRSS1 (0.48) | SMN1; SMN2NPC1GAARAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6504046-B1 | Cyclization of nitriles using acids, to form oxazolinone chemical intermediates such as 2-phenyl-4-isopropyl-4-methyl-1,3-oxazol-5-one, used as fungicides | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-07 | — | — | US | disclosed |
| CN-1304399-A | Process for preparation of amides | IHARA CHEMICAL IND CO (JP) | 2001-07-18 | — | — | CN | disclosed |
| EP-1092705-A1 | PROCESS FOR THE PREPARATION OF AMIDES | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |