Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272709 | 0.88 | CYP1A2 (0.39) | TP53MAOBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11179571 | 0.86 | SIGMAR1 (0.41) | TP53SMN1; SMN2EPHX2 | |
| SCHEMBL5073225 | 0.85 | EPHX2 (0.42) | TP53SMN1; SMN2EPHX2 | |
| SCHEMBL934485 | 0.83 | TP53 (0.44) | TP53MAOBCTSLCTSBRAB9A | |
| SCHEMBL8410057 | 0.82 | IDO1 (0.41) | RAB9ACYP1A2CYP3A4IDO1SMN1; SMN2 | |
| SCHEMBL5165136 | 0.78 | MAOB (0.52) | TP53MAOBCTSLCTSBCYP1A2 | |
| SCHEMBL8413003 | 0.76 | ACHE (0.43) | RAB9ANOS1POLB | |
| SCHEMBL2534699 | 0.73 | MAOB (0.46) | TP53MAOBCTSLCTSBCYP1A2 | |
| SCHEMBL8541497 | 0.72 | MAOB (0.50) | TP53MAOBCTSLCTSBCYP1A2 | |
| SCHEMBL8374191 | 0.72 | MAOB (0.50) | TP53MAOBCTSLCTSBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4393070-A | HYPOTENSIVE, VASODILATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-07-12 | — | — | US | disclosed |
| US-4307103-A | TREATMENT OF HYPERTENSION AND CARDIOVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-22 | — | — | US | disclosed |