Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11186707 | 1.00 | RAB9A (0.40) | RAB9ANPC1POLBALDH1A1HTT | |
| SCHEMBL11340248 | 0.84 | LMNA (0.49) | RAB9ANPC1POLBMAPTLMNA | |
| SCHEMBL11340240 | 0.84 | LMNA (0.49) | RAB9ANPC1POLBMAPTLMNA | |
| SCHEMBL11186402 | 0.83 | MAPK1 (0.43) | RAB9ANPC1POLBALDH1A1MAPT | |
| SCHEMBL11186406 | 0.83 | MAPK1 (0.43) | RAB9ANPC1POLBALDH1A1MAPT | |
| SCHEMBL11256810 | 0.83 | LMNA (0.41) | RAB9ANPC1POLBALDH1A1MAPT | |
| SCHEMBL11152011 | 0.83 | CA12 (0.48) | RAB9ALMNACNR1ACHEKCNH2 | |
| SCHEMBL11256806 | 0.83 | LMNA (0.41) | RAB9ANPC1POLBALDH1A1MAPT | |
| SCHEMBL11152007 | 0.83 | CA12 (0.48) | RAB9ALMNACNR1ACHEKCNH2 | |
| SCHEMBL10787431 | 0.81 | MAPK1 (0.41) | RAB9ANPC1POLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4423051-A | ANTIATHEROSCLEROTIC AGENTS AND HYPOLIPIDEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| US-4227014-A | ANTILIPEMIC AGENTS, ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-10-07 | — | — | US | disclosed |