Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256327 | 0.91 | PTGS2 (0.46) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL11154142 | 0.88 | PTGS2 (0.43) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL11170156 | 0.87 | PTGS1 (0.40) | LMNAHIF1APTGS1PTGS2CYP3A4 | |
| SCHEMBL11165820 | 0.85 | PTGS1 (0.38) | MEN1KMT2ALMNAHIF1APTGS1 | |
| SCHEMBL11191276 | 0.85 | MEN1 (0.37) | MEN1KMT2ALMNACYP1A2CYP2D6 | |
| SCHEMBL11199131 | 0.85 | MEN1 (0.37) | MEN1KMT2ALMNACYP1A2CYP2D6 | |
| Benzophenone SCHEMBL11256332 | 0.84 | LMNA (0.41) | MEN1KMT2ALMNACYP1A2CYP2D6 | |
| SCHEMBL11175333 | 0.84 | MEN1 (0.38) | MEN1KMT2ALMNACYP1A2CYP2D6 | |
| SCHEMBL11188751 | 0.83 | HRH3 (0.37) | MEN1KMT2APTGS1PTGS2TDP1 | |
| SCHEMBL11171928 | 0.82 | PTGS1 (0.39) | LMNACYP1A2CYP2D6HIF1APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024282-B1 | BENZOYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES | Dr. Karl Thomae GmbH (DE) | 1983-05-18 | — | — | EP | disclosed |