Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11182222 | 0.93 | HRH3 (0.36) | HRH3PTGS1PTGS2KMT2AMEN1 | |
| SCHEMBL11171930 | 0.92 | L3MBTL1 (0.39) | ABCB1PTGS1PTGS2KMT2AMEN1 | |
| SCHEMBL11261401 | 0.90 | PTGS2 (0.48) | HRH3ABCB1PTGS1PTGS2NPSR1 | |
| SCHEMBL11256561 | 0.90 | PTGS2 (0.48) | HRH3ABCB1PTGS1PTGS2NPSR1 | |
| SCHEMBL11271305 | 0.89 | PTGS2 (0.48) | HRH3PTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL11175678 | 0.88 | KDM4E (0.36) | HRH3ABCB1PTGS1PTGS2KMT2A | |
| SCHEMBL11166673 | 0.87 | KDM4E (0.36) | HRH3ABCB1PTGS1PTGS2KMT2A | |
| SCHEMBL11263518 | 0.87 | PTGS2 (0.44) | HRH3ABCB1PTGS1PTGS2KDM4E | |
| SCHEMBL11155210 | 0.87 | PTGS2 (0.44) | HRH3ABCB1PTGS1PTGS2KDM4E | |
| SCHEMBL11258342 | 0.86 | PTGS2 (0.45) | HRH3PTGS1PTGS2KDM4ESLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024282-B1 | BENZOYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES | Dr. Karl Thomae GmbH (DE) | 1983-05-18 | — | — | EP | disclosed |