Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11182928 | 0.99 | LMNA (0.60) | LMNAUSP2THRBKDM4EALDH1A1 | |
| SCHEMBL6908666 | 0.88 | MAPK1 (0.69) | LMNAUSP2THRBKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11183243 | 0.87 | MAPK1 (0.67) | LMNAUSP2THRBKDM4EALDH1A1 | |
| SCHEMBL6904661 | 0.86 | KDM4E (0.65) | LMNAUSP2THRBKDM4EALDH1A1 | |
| SCHEMBL6904904 | 0.86 | USP2 (0.66) | LMNAUSP2THRBKDM4EALDH1A1 | |
| SCHEMBL11191164 | 0.85 | ALDH1A1 (0.78) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11189440 | 0.85 | USP2 (0.65) | LMNAUSP2THRBKDM4EALDH1A1 | |
| SCHEMBL11191741 | 0.85 | KDM4E (0.80) | LMNAUSP2THRBKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11188368 | 0.84 | ALDH1A1 (0.77) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11178679 | 0.84 | KDM4E (0.78) | LMNAUSP2THRBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4370330-A | Method of enhancing circulation with piperazines | MERZ & COMPANY (DE) | 1983-01-25 | — | — | US | claimed |