Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 4/20 | 0.54 |
| ▸ | PPIB | P23284 | 1/20 | 0.54 |
| ▸ | PPIA | P62937 | 1/20 | 0.54 |
| ▸ | PPIG | Q13427 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8252663 | 0.90 | SMN1; SMN2 (0.54) | PPIDPPIBPPIAPPIGSMN1; SMN2 | |
| SCHEMBL3176370 | 0.87 | LMNA (0.51) | PPIDPPIBPPIAPPIGSMN1; SMN2 | |
| SCHEMBL21391612 | 0.87 | PPID (0.71) | PPIDPPIBPPIAPPIGSMN1; SMN2 | |
| SCHEMBL14477029 | 0.87 | PPID (0.51) | PPIDPPIBPPIAPPIGSMN1; SMN2 | |
| SCHEMBL13274881 | 0.87 | PPID (0.51) | PPIDPPIBPPIAPPIGSMN1; SMN2 | |
| SCHEMBL8003720 | 0.87 | MAPT (0.59) | PPIDPPIBPPIAPPIGSMN1; SMN2 | |
| SCHEMBL15692215 | 0.87 | KMT2A (0.61) | PPIDPPIBPPIAPPIGSMN1; SMN2 | |
| SCHEMBL75205 | 0.86 | PPID (0.69) | PPIDPPIBPPIAPPIGSMN1; SMN2 | |
| SCHEMBL6811685 | 0.86 | KMT2A (0.50) | SMN1; SMN2KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL1251880 | 0.85 | KDM4E (0.53) | PPIDPPIBPPIAPPIGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49700-E1 | Substituted nitrogen containing compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-17 | — | — | US | disclosed |
| EP-3210982-A1 | MODULATORS OF TOLL-LIKE RECEPTORS | Gilead Sciences, Inc. (US) | 2017-08-30 | — | — | EP | disclosed |
| EP-2818469-B1 | Intermediates for the preparation of modulators of toll-like receptors | GILEAD SCIENCES INC (US) | 2017-02-15 | — | — | EP | disclosed |
| US-7692014-B2 | Inhibitors of the HIV integrase enzyme | PFIZER, INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-4421693-A | INSECTICIDES, MITICIDES OR NEMATOCIDES | OTSUKA CHEMICAL CO., LTD. (JP) | 1983-12-20 | — | — | US | disclosed |
| US-4413005-A | 2,3-DIHYDRO-2,2-DIMETHYLBENZOFURAN-7-YL DERIVATIVES | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1983-11-01 | — | — | US | disclosed |