SCHEMBL21391612

SCHEMBL21391612

CCOC(=O)CNCc1ccc(N)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPID Q08752 7/20 0.71
PPIB P23284 2/20 0.71
PPIG Q13427 2/20 0.71
PPIA P62937 1/20 0.71
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
MAOA P21397 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.48
LTA4H P09960 4/20 0.46
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 1/20 0.43
KDM4E B2RXH2 1/20 0.43
HTT P42858 1/20 0.43
PPARG P37231 1/20 0.43
ANPEP P15144 1/20 0.42
ERAP2 Q6P179 1/20 0.42
CYP4F2 P78329 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8252663 0.87 SMN1; SMN2 (0.54) PPIDPPIBPPIGPPIALMNA
SCHEMBL11187635 0.87 PPID (0.54) PPIDPPIBPPIGPPIALMNA
SCHEMBL6326511 0.84 PPID (0.59) PPIDPPIBPPIGPPIALMNA
SCHEMBL22046135 0.84 PPID (0.59) PPIDPPIBPPIGPPIALMNA
SCHEMBL13274881 0.84 PPID (0.51) PPIDPPIBPPIGPPIALMNA
SCHEMBL3176370 0.84 LMNA (0.51) PPIDPPIBPPIGPPIALMNA
SCHEMBL14477029 0.84 PPID (0.51) PPIDPPIBPPIGPPIALMNA
SCHEMBL15692215 0.84 KMT2A (0.61) PPIDPPIBPPIGPPIALMNA
SCHEMBL8003720 0.84 MAPT (0.59) PPIDPPIBPPIGPPIALMNA
SCHEMBL75205 0.83 PPID (0.69) PPIDPPIBPPIGPPIASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111868618-B Liquid crystal aligning agent, polymer for obtaining the same, liquid crystal alignment film, and liquid crystal display element using the same 日产化学株式会社 2023-09-22 CN disclosed
CN-111868617-B Liquid crystal aligning agent, polymer for obtaining the same, liquid crystal alignment film, and liquid crystal display element using the same 日产化学株式会社 2023-09-12 CN disclosed
CN-111886270-B Polyurea copolymer, liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element using same 日产化学株式会社 2022-06-24 CN disclosed
CN-111886270-A Polyurea copolymer, liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element using same 日产化学株式会社 2020-11-03 CN disclosed
CN-111868618-A Liquid crystal aligning agent, polymer for obtaining the same, liquid crystal alignment film, and liquid crystal display element using the same 日产化学株式会社 2020-10-30 CN disclosed
CN-111868617-A Liquid crystal aligning agent, polymer for obtaining the same, liquid crystal alignment film, and liquid crystal display element using the same 日产化学株式会社 2020-10-30 CN disclosed
WO-2019182071-A1 LIQUID CRYSTAL ALIGNMENT AGENT, POLYMER FOR OBTAINING SAME, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学株式会社 2019-09-26 WO disclosed
WO-2019182070-A1 LIQUID CRYSTAL ALIGNING AGENT, POLYMER FOR OBTAINING SAME, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学株式会社 2019-09-26 WO disclosed
WO-2019182072-A1 POLYUREA COPOLYMER, LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学株式会社 2019-09-26 WO disclosed