Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11784620 | 0.86 | TSHR (0.31) | TSHR | |
| SCHEMBL11784222 | 0.84 | ABCB11 (0.32) | TSHR | |
| SCHEMBL9693959 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL29652096 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL31711467 | 0.73 | NR3C1 (0.32) | — | |
| SCHEMBL10887921 | 0.70 | ALDH1A1 (0.36) | TSHR | |
| SCHEMBL10887914 | 0.70 | ALDH1A1 (0.36) | TSHR | |
| SCHEMBL11159606 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL29737269 | 0.69 | TSHR (0.41) | TSHR | |
| SCHEMBL11219012 | 0.69 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077439-A2 | Process for the preparation of cyclohexene derivatives, and a starting product and intermediary products in this process | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-04-27 | — | — | EP | disclosed |